In RA the same immune system mistakenly attacks the patient's joints. Inflammation is thereby created & which causes the tissue lining the inside of joints (synovium) to thicken & result in pain & swelling in & around the affected joints. In case this inflammation goes unchecked, it can go on to damage cartilage which is the elastic tissue covering ends of bones within joints & sometimes the bone itself. Due to this loss of cartilage over time the spacing between bones inside joint can become smaller. Joints can therefore become unstable, loose & painful & lose their mobility as well. As a result joint deformity may also occur. Moreover, damage to joints cannot be reversed.
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